University of South-Eastern Norway
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Replication data for: Comparing ocular biometry and autorefraction measurements from the Myopia Master with the IOLMaster 700 and the Huvitz HRK-8000A autorefractor

Ocular biometry and autorefraction measured during cycloplegia with the three instruments: Myopia Master, IOLMaster 700 and Huvitz HRK-8000A. 


Purpose: To compare axial length (AL) and corneal radius (CR) measured with the OCULUS Myopia Master and the Zeiss IOLMaster 700, and cycloplegic refractive error measured with the Myopia Master and the Huvitz Auto Ref/Keratometer (HRK-8000A).  

Methods: The study included both eyes of 74 participants (16 males), with a mean age of 22.8 (3.7) years. Eyes were measured, during cycloplegia, with the three instruments: Myopia Master (AL, CR and refractive error), IOLMaster 700 (AL and CR) and HRK-8000A (CR and refractive error). Bland-Altman plots with mixed effects 95% limits of agreement (LoA) and corresponding 95% confidence intervals were used to assess the agreement in ocular biometry between the Myopia Master and the IOLMaster 700, and in refractive error between the Myopia Master and the HRK-8000A. 

Results: The analysis included 139 eyes, of which 52 were myopic (spherical equivalent refractive error, SER ≤ -0.50 D), 32 emmetropic and 55 hyperopic (SER ≥ 0.50 D). The 95% LoA for AL between the Myopia Master and IOLMaster 700 was -0.097–0.089 mm. There was no mean difference in AL [mean (SD) = -0.004 (0.047) mm, p = 0.34]. There was a significant difference in mean CR, with that measured with the Myopia Master being flatter than that measured with the IOLMaster 700 [0.035 (0.028) mm, p < 0.001]. The 95% LoA for CR was -0.02–0.09 mm. Compared with HRK-8000A, the Myopia Master measured a significantly more negative SER [-0.19 (0.33) D, p < 0.001], with 95% LoA of -0.86–0.46 D. 

Conclusion: The limits agreement in measurements of SER, CR, and AL when comparing the Myopia Master with HRK-8000A and the IOLMaster 700 were wider than deemed acceptable for making direct comparisons. This indicates that the instruments cannot be used interchangeably in clinical practice or research.


University of South-Eastern Norway


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